Delco Product Four

Barbiturates are a class of drugs that have been derived from barbituric acid. Barbituric acid itself has no therapeutic activity; however, its derivatives enhance the action of GABA, a neurotransmitter that inhibits the activity of nerve cells in the brain.

Historically, barbiturates were used in the treatment of anxiety, epilepsy, as anesthetics, and to induce sleep. However, they have a tendency to cause psychological and physical dependence and there is a fine line between a normal dose and a toxic dose. Nowadays, barbiturates have been largely superseded by safer drugs, although some are still used during surgery or to control seizures.